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Reverse Rett

RegisteredRegistered charity number 1136809ManchesterHealth and saving lives
Income£876k2025-12-31
Spending£677ksame year
Spent / received107%5-year average
Size in its cause88th pctHealth and saving lives
Registered2010Charitable company
Employees6latest return

Analysis

Reverse Rett is a registered charity in England and Wales, based in Manchester. It was registered in July 2010, 16 years ago. Its declared purposes cover the advancement of health or saving of lives, which this site groups under health and saving lives. Legally it is a charitable company (Companies House number 07278507). It says it sponsors or undertakes research.

In the financial year ending December 2025, Reverse Rett reported income of £876k and spending of £677k, leaving 23% of income unspent that year. Across the 5 years on record, from December 2021 to December 2025, income grew from £716k to £876k (+22%), an average of +5.2% a year. The sharpest change came in the year to December 2024, when income rose by 20%. Over the whole period it spent 107% of the income it received.

Among 24,651 England and Wales charities whose main cause is health and saving lives and that reported income, Reverse Rett sits at the 88th percentile: it is larger than about 88% of them. Against every charity in England and Wales with reported income it ranks in the 93rd percentile. Charities of a similar size with the same main cause include Lifelong Family Links (£875k), Cpotential Trust (£876k) and Shipston Home Nursing (£873k).

In its latest detailed accounts, income came from donations and legacies 53% and charitable activities 47%. Gifts in wills alone brought in £819. Charitable activities took 45% of spending and raising funds 54%. Reserves of £49k would cover about 1 months of spending at that rate. It employed 6 people.

Income and spending

£0£266k£533k£799k£1.1m2021 Income: £716,2942021 Spending: £853,34320212022 Income: £766,0382022 Spending: £1,065,83020222023 Income: £674,2762023 Spending: £764,34620232024 Income: £809,0952024 Spending: £764,34620242025 Income: £875,7822025 Spending: £677,4522025
IncomeSpending

Where the income comes from

  • Donations 53%
  • Legacies 0.1%
  • Charitable activities 47%

In the charity's own words

Reverse Rett is a patient advocacy and research organisation focused on delivering treatments and a cure for Rett syndrome and related MECP2 disorders.

Similar-sized charities, same cause

CharityLocationIncome
Lifelong Family LinksLondon£875k
Cpotential TrustLondon£876k
Shipston Home NursingWarwickshire£873k
Kent Sexual Assault & Abuse ServiceCanterbury£876k